Genesis Missions are generally easy. Players should not have any problem progressing over all. There is a point (Mission 3.1.16) where most players will need to complete several Kama Bingos before being able to progress.
Genesis functions as a tutorial and introduction to Master of Ives. Each mission provides information about the game, beginning with simple details and then diving into deeper complexities of gameplay, as well as explaining the game's lore. It is recommended that new players take the time to read these - though if you miss or forget any of it, it is all availble to be read at any time in game in the Handbook. The missions themselves serve to reinforce the information provided, starting with extremely simple missions and then becoming more complicated as you are expected to make use of the things you have learned. Even still, most of the missions should be fairly easy to complete.
Genesis is a critical part of the game. All other game modes begin locked and are unlocked as you complete Genesis missions. Genesis is the easiest part of the game and helps prepare you for the other game modes. It is recommended that you complete the first two chapters of Genesis before moving on to other game modes, and the first three chapters before starting The Towers.
Genesis is broken up into chapters, with an Ive featured as the Mission Ive for each chapter. Each chapter also includes three sex scenes featuring the Ive for that chapter.